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Remdesivir CAS No.:1809249-37-3

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Product details

Chemical Structure : GS-5734

CAS No.: 1809249-37-3

 

GS-5734 (GS 5734;GS5734;Remdesivir)

Catalog No.: URK-V1174  Only Used For Lab.

GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays.

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Biological Activity

GS-5734 (Remdesivir) is a monophosphoramidate prodrug of adenosine analogue that exhibits antiviral activity against multiple variants of EBOV (EC50=70-140 nM) and other filoviruses (EC50=0.019-1.48 uM) in cell-based assays.
GS-5734 (Remdesivir) suppresses EBOV replication and protects 100% of EBOV-infected animals against lethal disease, ameliorating clinical disease signs and pathophysiological markers.
GS-5734 (Remdesivir) is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro.

 

Physicochemical Properties

M.Wt

601.597

Formula

C28H36N5O8P

CAS No.

1809249-37-3

Storage

Solide Powder

-20 °C 3years;

4°C 2years

In Solvent

-80°C 6 Months

-20°C 1 Months

Solubility

10 mM in DMSO

Chemical Name

2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate

 

References

1. Warren TK, et al. Nature. 2016 Mar 17;531(7594):381-5.

2. Jacobs M, et al. Lancet. 2016 Jul 30;388(10043):498-503.

3. Siegel D, et al. J Med Chem. 2017 Mar 9;60(5):1648-1661.

URK-V1174_COA
URK-V1174_SDS
URK-V1174_TDS

 

Note: All products of Ureiko are only used for scientific research or drug certificate declaration, and we do not provide products and services for any personal use!

 

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